Nitrazepam has become related to extreme hepatic Conditions, just like other nitrobenzodiazepines. Nitrobenzodiazepines for example nitrazepam, nimetazepam, flunitrazepam, and clonazepam are more toxic to the liver than other benzodiazepines as they are metabolically activated by CYP3A4 which may result in cytotoxicity.When attempting to find subst